<!DOCTYPE html>
<html lang="en">
<head>
  <meta charset="UTF-8">
  <meta name="viewport" content="width=device-width, initial-scale=1.0">
  <meta http-equiv="X-UA-Compatible" content="ie=edge">
  <title>Document</title>
  <style>
    * {
      margin: 0;
      padding: 0
    }
    .bigblock {
      width: 960px;
      height: 600px;
      margin-left: 20px;
      margin-top: 20px;
      border: 1px solid #d6d6d6
    }
    .bigblock div{
      float: left;
      text-align: center
    }
    .haedpart {
      width: 960px;
      height: 50px;
      background-color: #4e9ce9;
    }
    .left {
      width: 150px;
      height: 500px;
      background-color: #d3e3e6;
    }
    .middle {
      width: 600px;
      height: 500px
      }
    .right {
      width: 208px;
      height: 500px;
      border: 1px solid #d5e4e7

    }
    .bottompart {
      width: 960px;
      height: 50px;
      background-color: #4e9ce9

    }

    .handmodecenter1 {
      margin-top: 16px
    }
    .handmodecenter2 {
      margin-top: 241px
    }
  </style>
</head>
<body>
  <div class="bigblock">
    <div class="haedpart">
      <p class="handmodecenter1">头部</p>
    </div>
    <div class="left">
      <p class="handmodecenter2">边侧道航</p>
    </div>
    <div class="middle">
      <p class="handmodecenter2">内容区域</p>
    </div>
    <div class="right">
      <p class="handmodecenter2">工具区域</p>
    </div>
    <div class="bottompart">
      <p class="handmodecenter1">页面底部</p>
    </div>
  </div>
</body>
</html>